Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147702 | 1.00 | POLB (0.45) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL8760557 | 1.00 | POLB (0.45) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL8760542 | 1.00 | POLB (0.45) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL8923231 | 0.86 | POLB (0.51) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL11743840 | 0.86 | POLB (0.44) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL26148678 | 0.84 | POLB (0.46) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL26148677 | 0.84 | POLB (0.46) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL26149447 | 0.83 | POLB (0.41) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL30908530 | 0.80 | IDO1 (0.56) | POLBPIN1CHRM4DRD2HTR7 | |
| SCHEMBL817976 | 0.80 | IDO1 (0.56) | POLBPIN1CHRM4DRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637738-A | Processes for preparing 1,2-epoxy-1,2,3,4-tetrahydronaphthalenes | ZENECA LIMITED (GB) | 1997-06-10 | — | — | US | disclosed |
| EP-0686153-B1 | CHEMICAL PROCESS FOR PREPARATION OF 1,2-EPOXY-1,2,3,4-TETRAHYDRNAPHTALENE | ZENECA LTD (GB) | 1997-06-04 | — | — | EP | disclosed |