Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26148284 | 0.85 | GABRA1 (0.44) | POLBMTNR1AMTNR1BIDO1GAA | |
| SCHEMBL9147702 | 0.83 | POLB (0.45) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL8760547 | 0.83 | POLB (0.45) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL8760542 | 0.83 | POLB (0.45) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL8760557 | 0.83 | POLB (0.45) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL8923231 | 0.82 | POLB (0.51) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL11743840 | 0.82 | POLB (0.44) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL26148678 | 0.81 | POLB (0.46) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL26148677 | 0.81 | POLB (0.46) | POLBPIN1MTNR1AMTNR1BCHRM4 | |
| SCHEMBL817976 | 0.76 | IDO1 (0.56) | POLBPIN1CHRM4DRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091957-A1 | PEPTIDE CONJUGATES OF PEPTIDIC TUBULIN INHIBITORS AS THERAPEUTICS | CYBREXA 4, INC. (US) | 2023-05-25 | — | — | WO | disclosed |