SCHEMBL8760757

SCHEMBL8760757

O=C1C2=CC(CCC2)C(=O)N1c1cc(OC2CC2)c(Br)cc1F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPOX P50336 5/20 0.35
SCD O00767 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760749 1.00 PPOX (0.35) PPOXSCD
SCHEMBL8761312 0.97 PPOX (0.39) PPOXSCD
SCHEMBL8761307 0.97 PPOX (0.39) PPOXSCD
SCHEMBL8759795 0.96 PPOX (0.38) PPOXSCD
SCHEMBL8759792 0.96 PPOX (0.38) PPOXSCD
SCHEMBL8760719 0.91 PPOX (0.33) PPOX
SCHEMBL8760723 0.91 PPOX (0.33) PPOX
SCHEMBL8763575 0.88 PPOX (0.47) PPOX
SCHEMBL8763570 0.88 PPOX (0.47) PPOX
SCHEMBL8760442 0.85 PPOX (0.34) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635485-B1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEM RES (JP) 1997-06-11 EP disclosed
US-5554581-A Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
US-5506190-A Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-04-09 US disclosed
EP-0635485-A1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-01-25 EP disclosed