SCHEMBL8760834

SCHEMBL8760834

O=C1C2=CC(CCC2)C(=O)N1c1cc(OC2CCCCC2)c(Cl)cc1F

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPOX P50336 14/20 0.51
SCN9A Q15858 1/20 0.39
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068389 1.00 PPOX (0.51) PPOXSCN9AHPGD
SCHEMBL9068388 1.00 PPOX (0.51) PPOXSCN9AHPGD
SCHEMBL8760828 1.00 PPOX (0.51) PPOXSCN9AHPGD
SCHEMBL8761614 0.99 PPOX (0.52) PPOXSCN9A
SCHEMBL8760695 0.99 PPOX (0.52) PPOXSCN9A
SCHEMBL8763575 0.96 PPOX (0.47) PPOXSCN9A
SCHEMBL8763570 0.96 PPOX (0.47) PPOXSCN9A
SCHEMBL8761210 0.90 PPOX (0.41) PPOXSCN9AHPGD
SCHEMBL8760528 0.90 PPOX (0.41) PPOXSCN9AHPGD
SCHEMBL8761206 0.90 PPOX (0.41) PPOXSCN9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635485-B1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEM RES (JP) 1997-06-11 EP disclosed
US-5554581-A Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
US-5506190-A Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-04-09 US disclosed
EP-0635485-A1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-01-25 EP disclosed