Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.73 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.65 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.64 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.64 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15891108 | 0.88 | BCHE (0.69) | BCHEFFAR1FFAR4 | |
| SCHEMBL7391510 | 0.88 | SPHK2 (0.82) | BCHESPHK2SPHK1GID4 | |
| SCHEMBL3498807 | 0.87 | BCHE (0.67) | BCHESPHK2SPHK1GID4 | |
| SCHEMBL7399120 | 0.85 | BCHE (0.65) | BCHESPHK2SPHK1GID4 | |
| SCHEMBL7396470 | 0.85 | GID4 (0.78) | SPHK2SPHK1GID4 | |
| SCHEMBL2295339 | 0.85 | BCHE (0.64) | BCHESPHK2SPHK1GID4 | |
| SCHEMBL7760590 | 0.85 | BCHE (1.00) | BCHE | |
| SCHEMBL11069984 | 0.85 | BCHE (1.00) | BCHE | |
| SCHEMBL7400144 | 0.84 | BCHE (0.63) | BCHESPHK2SPHK1GID4 | |
| SCHEMBL5099013 | 0.83 | GID4 (0.65) | BCHESPHK2SPHK1GID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767800-A1 | HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000736-A1 | HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |
| EP-0668270-A2 | 2-Imidazoline-5-ones derivatives as fungicides | RHONE-POULENC AGROCHIMIE (FR) | 1995-08-23 | — | — | EP | disclosed |