Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521374 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL5822101 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8760759 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8761293 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL38575 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL39189 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL1906472 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL38564 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8760847 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8683870 | 1.00 | GPR84 (0.40) | GPR84ESR1PTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406169-B1 | 2,4-Dimethyl-6-s-alkyl-phenols | CIBA GEIGY (CH) | 1997-06-04 | — | — | EP | disclosed |
| US-5098945-A | Stabilizers for organic materials against heat, oxidation and actinic degradation | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0406169-A1 | 2,4-Dimethyl-6-s-alkyl-phenols | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |