Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959543 | 0.90 | NPC1 (0.53) | L3MBTL1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL12072153 | 0.78 | NPC1 (0.57) | L3MBTL1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL9674957 | 0.76 | NPC1 (0.56) | L3MBTL1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL28869659 | 0.75 | AKR1B1 (0.48) | L3MBTL1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL9390392 | 0.74 | L3MBTL1 (0.37) | L3MBTL1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1543938 | 0.72 | TP53 (0.56) | L3MBTL1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL1543904 | 0.72 | KCNH2 (0.51) | L3MBTL1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1545207 | 0.70 | NOTUM (0.51) | L3MBTL1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1544194 | 0.70 | NPC1 (0.54) | L3MBTL1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL120396 | 0.69 | NOTUM (0.68) | L3MBTL1NPC1RAB9ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590415-B1 | 1,2,4-Oxadiazole derivatives for controlling endoparasites | BAYER AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5428047-A | Nematocides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0590415-A2 | 1,2,4-Oxadiazole derivatives for controlling endoparasites | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |