Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761149 | 0.99 | TSHR (0.39) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8760937 | 0.98 | LMNA (0.39) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8752131 | 0.84 | LMNA (0.42) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL333577 | 0.81 | LMNA (0.45) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8726308 | 0.78 | LMNA (0.41) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL371082 | 0.77 | LMNA (0.46) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8814469 | 0.77 | LMNA (0.50) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8752124 | 0.76 | LMNA (0.39) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL332721 | 0.75 | LMNA (0.44) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9076702 | 0.75 | LMNA (0.44) | TSHRLMNASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767779-A1 | ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS | NanoSystems L.L.C. (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000211-A1 | ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS | NANOSYSTEMS L.L.C. (US) | 1996-01-04 | — | — | WO | claimed |
| EP-0767779-A1 | ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS | NanoSystems L.L.C. (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000211-A1 | ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS | NANOSYSTEMS L.L.C. (US) | 1996-01-04 | — | — | WO | disclosed |