Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278571 | 0.82 | ESR1 (0.54) | ESR1ESR2PDCD1CD274KDM4E | |
| SCHEMBL8760147 | 0.81 | ESR2 (0.52) | ESR1ESR2PDCD1CD274MEN1 | |
| SCHEMBL8760964 | 0.79 | LTA4H (0.58) | ACACBSLC6A2SLC6A3CYP1A2CYP2C19 | |
| SCHEMBL57369 | 0.78 | MEN1 (0.57) | ESR1ESR2PDCD1CD274MEN1 | |
| Hydroquinone SCHEMBL28076396 | 0.78 | MEN1 (0.57) | ESR1ESR2PDCD1CD274MEN1 | |
| SCHEMBL18412109 | 0.78 | ACACB (0.41) | ACACBCTSLCTSKSLC6A2SLC6A3 | |
| SCHEMBL28450063 | 0.77 | ESR1 (0.48) | ESR1ESR2PDCD1CD274MEN1 | |
| SCHEMBL120897 | 0.76 | ESR1 (0.44) | ESR1ESR2PDCD1CD274MEN1 | |
| SCHEMBL16922414 | 0.75 | ESR1 (0.40) | ESR1ESR2PDCD1CD274MEN1 | |
| SCHEMBL16181733 | 0.75 | ACACB (0.39) | MEN1KMT2AACACBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497465-B1 | Record material | APPLETON PAPER INC (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0497465-A1 | Record material | APPLETON PAPERS INC. (US) | 1992-08-05 | — | — | EP | disclosed |