Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761204 | 0.89 | KDM4E (0.51) | NQO1MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL12747979 | 0.76 | KDM4E (0.62) | NQO1KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL7354341 | 0.72 | KDM4E (0.55) | NQO1KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL7362388 | 0.71 | CA12 (0.48) | NQO1MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL1095043 | 0.70 | KDM4E (0.57) | NQO1KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8945546 | 0.70 | NQO1 (0.59) | NQO1VKORC1CYP2C9TOP2A | |
| SCHEMBL8945547 | 0.69 | NQO1 (0.55) | NQO1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL27752675 | 0.68 | KDM4E (0.62) | NQO1KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL12028898 | 0.67 | NQO1 (1.00) | NQO1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL28202633 | 0.67 | NQO1 (0.56) | NQO1KDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553590-B1 | Antithrombotics derived from coumarin and process for obtaining them. | ROVI LAB FARMACEUT SA (ES) | 1997-06-04 | — | — | EP | claimed |