Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | NQO1 | P15559 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379994 | 0.82 | KDM4E (0.69) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL29872 | 0.82 | KDM4E (0.69) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL7737431 | 0.82 | KDM4E (0.69) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL2540914 | 0.82 | ALDH1A1 (0.53) | KDM4ENQO1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL8701572 | 0.80 | KDM4E (0.67) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL5713261 | 0.78 | KDM4E (0.65) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL23727919 | 0.77 | KDM4E (0.62) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL29695571 | 0.77 | KDM4E (1.00) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL5459905 | 0.77 | KDM4E (1.00) | KDM4ENQO1ALDH1A1LMNATP53 | |
| SCHEMBL11693383 | 0.77 | GAA (0.69) | KDM4ENQO1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-110357891-A | The 2- hydroxypyrrole derivatives and its synthetic method and application that chromone base replaces | 云南大学 | 2019-10-22 | — | — | CN | disclosed |
| CN-104428036-A | Polypeptides and their use | NOVABIOTICS LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-101501015-A | Use of coumarin derivatives in antifungal therapy | NOVABIOTICS LTD (GB) | 2009-08-05 | — | — | CN | disclosed |