Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760152 | 0.85 | MAPT (0.35) | L3MBTL1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL13116695 | 0.68 | NPC1 (0.51) | L3MBTL1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8761458 | 0.68 | EGFR (0.42) | L3MBTL1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11345797 | 0.67 | L3MBTL1 (0.37) | L3MBTL1HDAC8MAPK1TDP1TSHR | |
| SCHEMBL13141061 | 0.65 | — | — | |
| SCHEMBL8760748 | 0.65 | L3MBTL1 (0.46) | L3MBTL1HDAC1HDAC8HDAC6MAPK1 | |
| SCHEMBL8760854 | 0.63 | STAT3 (0.42) | L3MBTL1HDAC1HDAC8HDAC6MAPK1 | |
| SCHEMBL4000246 | 0.62 | SMN1; SMN2 (0.46) | L3MBTL1HDAC1HDAC8HDAC6TDP1 | |
| SCHEMBL15474232 | 0.62 | MAOB (0.43) | L3MBTL1HDAC1HDAC8HDAC6MAPK1 | |
| SCHEMBL12284250 | 0.61 | L3MBTL1 (0.35) | L3MBTL1CYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590415-B1 | 1,2,4-Oxadiazole derivatives for controlling endoparasites | BAYER AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5428047-A | Nematocides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0590415-A2 | 1,2,4-Oxadiazole derivatives for controlling endoparasites | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |