SCHEMBL8761646

SCHEMBL8761646

N[C@@H](CC(=O)O)C(=O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.61
ACE P12821 3/20 0.56
CPA1 P15085 3/20 0.56
ACE2 Q9BYF1 3/20 0.56
NAALAD2 Q9Y3Q0 1/20 0.55
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29525004 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL10618864 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL30494635 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL135367 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL668395 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL11548564 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL135366 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL8206518 0.98 MME (0.60) MMEACECPA1ACE2NAALAD2
Water SCHEMBL27822843 0.98 MME (0.60) MMEACECPA1ACE2NAALAD2
Hydrochloric Acid SCHEMBL9136406 0.98 MME (0.60) MMEACECPA1ACE2NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220167645-A1 METHODS OF IMPROVING FISH FEED CONVERSION RATE AND SURVIVAL AQUINOVO LTD. (IL) 2022-06-02 US claimed
WO-2022072356-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2022-04-07 WO claimed
EP-0581032-B1 Method for production of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride AJINOMOTO KK (JP) 1997-06-11 EP claimed
US-5371269-A Crystallization from aqueous solution containing hydrochloric acid and methanol AJINOMOTO CO., INC. (JP) 1994-12-06 US claimed
EP-0581032-A1 Method for production of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride Ajinomoto Co., Inc. (JP) 1994-02-02 EP claimed
EP-0256812-B1 PROCESS FOR SEPARATION OF N-PROTECTED ALPHA-L-ASPARTYL-L-PHENYLALANINES Ajinomoto Co., Inc. (JP) 1992-12-09 EP claimed
US-4677126-A Oxa-fenchyl esters and amides of alpha-L-aspartyl-D-phenylglycine THE PROCTER & GAMBLE COMPANY (US) 1987-06-30 US claimed
EP-0168881-A1 Oxa-fenchyl esters and amides of alpha-l-aspartyl-d-phenylglycine THE PROCTER & GAMBLE COMPANY (US) 1986-01-22 EP claimed
JP-6073091-A None JP disclosed
JP-63044594-A None JP disclosed
EP-4499111-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2025-02-05 EP disclosed
CN-106661088-B Neurokinin B antagonists in fish reproduction 耶路撒冷希伯来大学伊萨姆研究发展有限公司 2024-06-21 CN disclosed
WO-2023192828-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2023-10-05 WO disclosed
US-20220167645-A1 METHODS OF IMPROVING FISH FEED CONVERSION RATE AND SURVIVAL AQUINOVO LTD. (IL) 2022-06-02 US disclosed
US-4692512-A FOODS AND BEVERAGES THE PROCTER & GAMBLE COMPANY (US) 1987-09-08 US disclosed
US-4677126-A Oxa-fenchyl esters and amides of alpha-L-aspartyl-D-phenylglycine THE PROCTER & GAMBLE COMPANY (US) 1987-06-30 US disclosed
EP-0168881-A1 Oxa-fenchyl esters and amides of alpha-l-aspartyl-d-phenylglycine THE PROCTER & GAMBLE COMPANY (US) 1986-01-22 EP disclosed
EP-0168112-A2 Alpha-L-aspartyl-D-phenylglycine esters and amides useful as high intensity sweeteners THE PROCTER & GAMBLE COMPANY (US) 1986-01-15 EP disclosed
JP-H00673091-A 0001-01-01 JP disclosed
JP-S06344594-A 0001-01-01 JP disclosed