SCHEMBL668395

SCHEMBL668395

NC(CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.61
ACE P12821 3/20 0.56
CPA1 P15085 3/20 0.56
ACE2 Q9BYF1 3/20 0.56
NAALAD2 Q9Y3Q0 1/20 0.55
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29525004 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL10618864 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL30494635 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL135367 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL11548564 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL135366 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL8761646 1.00 MME (0.61) MMEACECPA1ACE2NAALAD2
SCHEMBL8206518 0.98 MME (0.60) MMEACECPA1ACE2NAALAD2
Water SCHEMBL27822843 0.98 MME (0.60) MMEACECPA1ACE2NAALAD2
Hydrochloric Acid SCHEMBL9136406 0.98 MME (0.60) MMEACECPA1ACE2NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628819-B A kind of technique that coupling reaction generates Aspartame 常茂生物化学工程股份有限公司 2019-05-21 CN claimed
CN-107076753-B Specific biomarker composition for obese people and application thereof 深圳华大基因科技有限公司 2019-01-18 CN claimed
WO-2017189528-A1 CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME Ecolab USA, Inc. (US) 2017-11-02 WO claimed
CN-107076753-A Obese people specific biological marking composition and application thereof 深圳华大基因科技有限公司 2017-08-18 CN claimed
CN-1615359-B Method for producing L-amino acid using bacterium belonging to genus Escherichia AJINOMOTO KK 2010-04-28 CN claimed
EP-1261623-A4 NEW RETINOL DERIVATIVES, THE METHOD OF PREPARATIONS AND THE USES THEREOF CHEBIGEN INC (KR) 2007-04-25 EP claimed
US-7030265-B2 Retinol derivatives, the method of preparations and the uses thereof CHEBIGEN, INC. (KR) 2006-04-18 US claimed
US-20040023888-A1 Retinol derivatives, the method of preparations and the uses thereof CHEBIGEN INC. (KR) 2004-02-05 US claimed
CN-1455780-A novel retinol derivatives, preparation method and use thereof CHEBIGEN INC (KR) 2003-11-12 CN claimed
EP-1261623-A1 NEW RETINOL DERIVATIVES, THE METHOD OF PREPARATIONS AND THE USES THEREOF Chebigen Inc. (KR) 2002-12-04 EP claimed
WO-1998008919-A2 NOVEL WATER SOLUBLE METAL WORKING FLUIDS SOLUTIA INC. (US) 1998-03-05 WO claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
EP-0307496-B1 PROCESS FOR THE PRODUCTION OF N-FORMYL-ASPARTYL-PHENYLALANINE OR ITS METHYL ESTER AJINOMOTO CO., INC. (JP) 1993-06-30 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
WO-1992000953-A1 A ONE-POT PROCESS FOR THE PREPARATION OF ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER HYDROCHLORIDE THE NUTRASWEET COMPANY (US) 1992-01-23 WO claimed
EP-0307496-A1 Process for the production of N-formyl-aspartyl-phenylalanine or its methyl ester AJINOMOTO CO., INC. (JP) 1989-03-22 EP claimed
EP-0214941-A2 Method for the removal of the formyl group from an ester of an N-formyl peptide or N-formyl aminoacid LARK S.p.A. (IT) 1987-03-18 EP claimed
EP-0196866-A2 Preparation process of alpha-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-10-08 EP claimed
EP-0048345-A1 Process for the preparation of an alpha-L-aspartyl-L-phenylalanine-alkyl ester CHIMICASA GMBH (CH) 1982-03-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023888-A1 Retinol derivatives, the method of preparations and the uses thereof RBP4, RBP1, ADH4 MME 1400/4885ACE 2044/4885CPA1 1988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.