Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.98 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.98 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545380 | 1.00 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL5674183 | 1.00 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL29878305 | 0.99 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3078699 | 0.99 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3078695 | 0.99 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10366431 | 0.99 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10366430 | 0.99 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10366870 | 0.98 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10366871 | 0.98 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL13828279 | 0.89 | OPRM1 (0.78) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632806-B1 | AMINOCYCLOHEXYLAMIDES FOR ANTIARRHYTHMIC AND ANAESTHETIC USES | UNIV BRITISH COLUMBIA (CA) | 1997-07-02 | — | — | EP | claimed |
| EP-0632806-B1 | AMINOCYCLOHEXYLAMIDES FOR ANTIARRHYTHMIC AND ANAESTHETIC USES | UNIV BRITISH COLUMBIA (CA) | 1997-07-02 | — | — | EP | disclosed |
| US-5506257-A | SODIUM CHANNEL BLOCKERS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1996-04-09 | — | — | US | disclosed |