SCHEMBL876216

SCHEMBL876216

COn1cccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784162 0.77 KDM4E (0.36)
SCHEMBL9467993 0.75
SCHEMBL1829631 0.74 POLB (0.33)
SCHEMBL18399020 0.74
SCHEMBL2840373 0.72
SCHEMBL11038490 0.72
SCHEMBL19917479 0.72
SCHEMBL2050240 0.72
SCHEMBL3970016 0.71 FDPS (0.31)
Hydrochloric Acid SCHEMBL28226758 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111285864-B Preparation and application of p-chlorophenyl isoxazole methoxy pyrazole derivative containing isoxazole heterocyclic unit 南通大学 2022-10-11 CN claimed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP claimed
US-20250382304-A1 HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS NUVALENT INC (US) 2025-12-18 US disclosed
US-20250304567-A1 PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2025-10-02 US disclosed
US-20250282768-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2025-09-11 US disclosed
US-12275742-B2 Heteroaromatic macrocyclic ether chemotherapeutic agents NUVALENT, INC. (US) 2025-04-15 US disclosed
CN-119497713-A USP1 inhibitors 上海齐鲁制药研究中心有限公司 2025-02-21 CN disclosed
US-12202826-B2 N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway REDX PHARMA PLC (GB) 2025-01-21 US disclosed
US-12091399-B2 Phenyltetrazole derivatives as plasma kallikrein inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-09-17 US disclosed
US-12024510-B2 Pyrazolopyridine-diamides, their use as insecticide and processes for preparing the same PI INDUSTRIES LTD. (IN) 2024-07-02 US disclosed
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG SHIONOGI & CO., LTD. (JP) 2024-06-06 US disclosed
EP-0873318-A1 HETEROCYCLICALLY SUBSTITUTED SALICYLIC ACID DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed
EP-0796259-A2 NOVEL PYRIMIDINYLOXY- AND PYRIMIDINYLAMINO-ETHYLPHENYL-DIOXOLANE DERIVATIVES Novartis AG (CH) 1997-09-24 EP disclosed
EP-0619374-B1 Colorimetric determination of an analyte using benzyl alcohol dehydrogenase and a chromogenic redox-indicator BOEHRINGER MANNHEIM GMBH (DE) 1997-08-13 EP disclosed
WO-1997012879-A1 HETEROCYCLICALLY SUBSTITUTED SALICYLIC ACID DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1997-04-10 WO disclosed
WO-1997009316-A1 4-[2-(PYRIMIDIN-4-OXY- OR 4-YLAMINO)-ETHYL]-PHENYL-OXIMES NOVARTIS AG (CH) 1997-03-13 WO disclosed
WO-1996017843-A2 NOVEL PYRIMIDINYLOXY- AND PYRIMIDINYLAMINO-ETHYLPHENYL-DIOXOLANE DERIVATIVES NOVARTIS AG (CH) 1996-06-13 WO disclosed
EP-0619374-A2 Colorimetric determination of an analyte using benzyl alcohol dehydrogenase and a chromogenic redox-indicator Roche Diagnostics GmbH (DE) 1994-10-12 EP disclosed
EP-0043917-B1 ESTERS OF N-ACYLATED-N-METHYL-0-PYRAZOL(4)YL-CARBAMIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS BIOCIDES BAYER AG (DE) 1984-10-24 EP disclosed
EP-0007080-A1 Process for the preparation of N-azolylmethyl-substituted haloacetanilides BASF Aktiengesellschaft (DE) 1980-01-23 EP disclosed