SCHEMBL8762166

SCHEMBL8762166

Nc1ccc(Oc2ccccc2C(c2ccccc2Oc2ccc(N)cc2F)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
AR P10275 2/20 0.37
PARP10 Q53GL7 1/20 0.37
MAOA P21397 1/20 0.37
HSPB1 P04792 1/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.35
MAPK14 Q16539 1/20 0.35
MITF O75030 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NLRP1 Q9C000 1/20 0.35
NOD2 Q9HC29 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
NLRP3 Q96P20 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8762652 0.93 MEN1 (0.38) ARHSPB1MEN1KMT2AALDH1A1
SCHEMBL8762383 0.90 MAOB (0.42) ARMEN1KMT2AALDH1A1MAPT
SCHEMBL8761225 0.88 NCOA1 (0.40) NCOA1NCOA3ARMAOAMEN1
SCHEMBL721404 0.87 NCOA1 (0.49) NCOA1NCOA3ARMAOAMEN1
SCHEMBL8762371 0.86 AR (0.39) NCOA1NCOA3ARMAOAMEN1
SCHEMBL8762093 0.85 NCOA1 (0.40) NCOA1NCOA3ARPARP10MAOA
SCHEMBL8762685 0.84 NCOA1 (0.39) NCOA1NCOA3ARPARP10MAOA
SCHEMBL1683859 0.84 MAOB (0.50) NCOA1NCOA3ARMAOAMEN1
SCHEMBL8761191 0.82 MEN1 (0.38) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL8762403 0.82 AR (0.36) ARMAOAMAPTGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499159-B1 Liquid crystal device and dislay apparatus CANON KK (JP) 1997-05-07 EP disclosed
US-5419932-A Polyamide alignment film CANON KABUSHIKI KAISHA (JP) 1995-05-30 US disclosed
EP-0499159-A2 Liquid crystal device and dislay apparatus CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed