SCHEMBL8762186

SCHEMBL8762186

O=C(O)CC(CC(=O)O)(OC(=O)OC(CC(=O)O)(CC(=O)O)C(=O)O)C(=O)O.[CaH2].[CaH2].[CaH2].[CaH2]

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
ACLY P53396 3/20 0.33
CPT2 P23786 2/20 0.32
KDM4E B2RXH2 1/20 0.30
FFAR1 O14842 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6055783 1.00 ALDH1A1 (0.40) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL28025181 0.98 ALDH1A1 (0.39) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL5809750 0.97 ALDH1A1 (0.42) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL8442298 0.95 ALDH1A1 (0.40) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL28799874 0.95 ALDH1A1 (0.40) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
Ammonia Solution, Strong SCHEMBL29089408 0.93 ALDH1A1 (0.39) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
Citric Acid SCHEMBL27538183 0.87 ALDH1A1 (0.62) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL8352054 0.85 CYP2C19 (0.44) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL10621210 0.85 CYP2C19 (0.44) ALDH1A1CYP2C19HIF1ACYP2D6TSHR
SCHEMBL10476520 0.84 TSHR (0.39) ALDH1A1CYP2C19HIF1ACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114711432-A Water-soluble calcium and preparation method thereof, calcium agent and application of water-soluble calcium 云南莱德福科技有限公司 2022-07-08 CN claimed
CN-108434126-A Treat the dry powder formulation and method of tuberculosis 普马特里克斯营业公司 2018-08-24 CN disclosed
EP-0782443-A1 PHARMACEUTICAL FORMULATIONS COMPRISING CLAVULANIC ACID OR DERIVATIVES AND AN ORGANIC ACID OR SALT SMITHKLINE BEECHAM PLC (GB) 1997-07-09 EP disclosed
WO-1996007408-A1 PHARMACEUTICAL FORMULATIONS COMPRISING CLAVULANIC ACID OR DERIVATIVES AND AN ORGANIC ACID OR SALT SMITHKLINE BEECHAM PLC (GB) 1996-03-14 WO disclosed