Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.56 |
| ▸ | FNTB | P49356 | 14/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865645 | 0.95 | FNTA (0.61) | FNTAFNTBAPOBEC3GTSHR | |
| SCHEMBL8763257 | 0.95 | FNTA (0.63) | FNTAFNTBNTSR1 | |
| SCHEMBL9058050 | 0.93 | FNTA (0.56) | FNTAFNTBNTSR1 | |
| SCHEMBL8763006 | 0.91 | FNTA (0.59) | FNTAFNTBAPOBEC3GTSHR | |
| SCHEMBL8763050 | 0.90 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL9068133 | 0.90 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL8866072 | 0.90 | FNTA (0.69) | FNTAFNTB | |
| SCHEMBL8763284 | 0.89 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL8865542 | 0.88 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL9060165 | 0.88 | FNTA (0.62) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010034-A2 | THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | claimed |
| US-5652257-A | ANTICARCINOGENIC | MERCK & CO., INC. (US) | 1997-07-29 | — | — | US | disclosed |
| EP-0783517-A2 | THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010034-A2 | THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |