SCHEMBL9058050

CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)O)Cc1ccccc1)NC(=O)Cc1cncn1Cc1ccc2ccccc2c1.CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccnc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	18/20	0.56

▸	FNTB	P49356	18/20	0.56

▸	NTSR1	P30989	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9068133	0.94	FNTA (0.61)	FNTAFNTB
SCHEMBL9060165	0.93	FNTA (0.62)	FNTAFNTB
SCHEMBL8762248	0.93	FNTA (0.56)	FNTAFNTBNTSR1
SCHEMBL8763050	0.92	FNTA (0.59)	FNTAFNTB
SCHEMBL8763257	0.92	FNTA (0.63)	FNTAFNTBNTSR1
SCHEMBL9060561	0.91	FNTA (0.58)	FNTAFNTB
SCHEMBL8763043	0.90	FNTA (0.67)	FNTAFNTB
SCHEMBL8865645	0.89	FNTA (0.61)	FNTAFNTB
SCHEMBL8763048	0.89	FNTA (0.51)	FNTAFNTB
SCHEMBL8763006	0.87	FNTA (0.59)	FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1996010034-A2	THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE	MERCK & CO., INC. (US)	1996-04-04	—	—	WO	disclosed