Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872022 | 1.00 | MME (0.43) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL5405883 | 1.00 | MME (0.43) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL5871974 | 0.91 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5871880 | 0.91 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2842137 | 0.86 | HPGD (0.43) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL5871924 | 0.85 | PSEN1 (0.46) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL5404893 | 0.83 | LAP3 (0.47) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8159887 | 0.83 | LAP3 (0.47) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL14524365 | 0.82 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12992322 | 0.82 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769936-A1 | SELF-EMULSIFYING DRUG DELIVERY SYSTEM | G.D. SEARLE & CO. (US) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996003113-A1 | SELF-EMULSIFYING DRUG DELIVERY SYSTEM | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |