Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762463 | 0.84 | GBA1 (0.42) | GBA1ALDH1A1SMN1; SMN2LMNAHIF1A | |
| SCHEMBL11750035 | 0.80 | EPHX1 (0.40) | KMT2ALMNAEPHX1HIF1A | |
| SCHEMBL8762460 | 0.79 | GBA1 (0.39) | GBA1ALDH1A1SMN1; SMN2LMNAHIF1A | |
| SCHEMBL2860264 | 0.76 | GBA1 (0.43) | GBA1ALDH1A1SMN1; SMN2LMNAHIF1A | |
| SCHEMBL8761376 | 0.76 | GBA1 (0.37) | GBA1HTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5165244 | 0.71 | GBA1 (0.43) | GBA1ALDH1A1SMN1; SMN2LMNAHIF1A | |
| SCHEMBL8762856 | 0.71 | HTT (0.46) | HTTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9245208 | 0.67 | TAAR1 (0.50) | GBA1ALDH1A1SMN1; SMN2LMNAHIF1A | |
| SCHEMBL9723603 | 0.67 | GBA1 (0.36) | GBA1 | |
| SCHEMBL27738631 | 0.66 | EPHX1 (0.54) | ALDH1A1EPHX1HIF1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638066-B1 | Process for the preparation of a tertiary-aryl carbotiimide and alternating polycarbodiimide | DU PONT (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5352400-A | Carbodiimides and processes therefor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5349087-A | Carbodiimides and processes therefor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-09-20 | — | — | US | disclosed |