SCHEMBL8763003

SCHEMBL8763003

CNC(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.58
GRM6 O15303 1/20 0.58
GRIN2D O15399 1/20 0.58
GRIN3B O60391 1/20 0.58
GSR P00390 1/20 0.58
CYP1A2 P05177 1/20 0.58
GRIK1 P39086 1/20 0.58
GRM5 P41594 1/20 0.58
GRIA1 P42261 1/20 0.58
GRIA2 P42262 1/20 0.58
GRIA3 P42263 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58
SLC1A1 P43005 1/20 0.58
GRIA4 P48058 1/20 0.58
GRIN1 Q05586 1/20 0.58
GRIN2A Q12879 1/20 0.58
GRIK2 Q13002 1/20 0.58
GRIK3 Q13003 1/20 0.58
GRIN2B Q13224 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85942 1.00 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL24140515 1.00 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL25551968 0.85 BMP1 (0.59) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL19088203 0.84 DPP4 (0.51) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL14669745 0.84 BMP1 (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL14669847 0.84 BMP1 (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL14669954 0.84 BMP1 (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL17793306 0.84 BMP1 (0.57) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL5198617 0.83 DPP4 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL5198619 0.83 DPP4 (0.54) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58170703-A None JP disclosed
CN-115786286-A Gamma-glutamine synthetase mutant, recombinant thereof and application of mutant in continuous catalysis coupled with ATP regeneration system 大连医诺生物股份有限公司 2023-03-14 CN disclosed
CN-114213276-A Method for extracting and purifying theanine from enzyme catalytic reaction 翁源广业清怡食品科技有限公司 2022-03-22 CN disclosed
US-20150010970-A1 METHODS FOR PRODUCING END-PRODUCTS FROM CARBON SUBSTRATES DANISCO US INC. (US) 2015-01-08 US disclosed
EP-0784629-A1 PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES Chiroscience Limited (GB) 1997-07-23 EP disclosed
WO-1996011209-A1 PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES CHIROSCIENCE LIMITED (GB) 1996-04-18 WO disclosed
WO-1994007527-A2 VASOACTIVE PEPTIDE INHIBITION BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1994-04-14 WO disclosed
JP-S58170703-A QUALITY IMPROVEMENT IN GREEN TEA CHUO KASEI KK 1983-10-07 JP disclosed
EP-0014984-B1 GLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1982-12-01 EP disclosed