Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64942 | 0.91 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL791032 | 0.89 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL27884442 | 0.86 | KDM4C (0.42) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL29468138 | 0.86 | KDM4C (0.37) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL22774009 | 0.84 | LMNA (0.53) | LMNAL3MBTL1MAPTMEN1CYP3A4 | |
| SCHEMBL22775401 | 0.84 | KDM4C (0.41) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL22774783 | 0.84 | LMNA (0.44) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL22775174 | 0.84 | LMNA (0.58) | LMNAMAPTMEN1KMT2ADGKA | |
| SCHEMBL248421 | 0.84 | KDM4C (0.41) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL22775059 | 0.84 | LMNA (0.48) | KDM4CKDM4APHF8KDM2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779821-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | Marsden, John Christopher (GB) | 1997-06-25 | — | — | EP | disclosed |
| WO-1996007434-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1996-03-14 | — | — | WO | disclosed |