SCHEMBL8763181

SCHEMBL8763181

CC1C(C)C1(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.42
ESR1 P03372 7/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 3/20 0.42
LMNA P02545 3/20 0.42
CYP3A4 P08684 3/20 0.42
HSD17B10 Q99714 3/20 0.42
ALOX15 P16050 3/20 0.42
ALDH1A1 P00352 2/20 0.42
RECQL P46063 2/20 0.42
TYR P14679 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HIF1A Q16665 2/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42
GMNN O75496 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18932628 0.90 ESR2 (0.40) ESR2ESR1HPGDMAPTLMNA
SCHEMBL14039289 0.88 ESR2 (0.39) ESR2ESR1HPGDMAPTLMNA
SCHEMBL12457781 0.78 ESR2 (0.43) ESR2ESR1HPGDMAPTLMNA
SCHEMBL16582069 0.75 KDM1A (0.40) ESR2ESR1LMNAALDH1A1ACHE
SCHEMBL30669849 0.73 ESR1 (0.38) ESR2ESR1HPGDMAPTLMNA
SCHEMBL13379642 0.72 ESR2 (0.44) ESR2ESR1HPGDMAPTLMNA
SCHEMBL13275920 0.70 ESR2 (0.44) ESR2ESR1HPGDMAPTLMNA
SCHEMBL13227324 0.69 ESR2 (0.39) ESR2ESR1HPGDMAPTLMNA
SCHEMBL13379644 0.67 ESR2 (0.45) ESR2ESR1HPGDMAPTLMNA
SCHEMBL175542 0.67 HSD11B1 (0.41) ESR2ESR1HPGDMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993208-B2 Foil transferring method and toner for forming foil transferring layer KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2015-03-31 US disclosed
US-20120264045-A1 FOIL TRANSFERRING METHOD AND TONER FOR FORMING FOIL TRANSFERRING LAYER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC,. (JP) 2012-10-18 US disclosed
EP-0333498-B1 Process for preparation of a gelled polyester for toner MITSUBISHI RAYON CO (JP) 1997-07-16 EP disclosed
US-4980448-A OFFSET AND BLOCKING RESISTANCE; SELF-CHARGING; SHARP COPIED IMAGES MITSUBISHI RAYON COMPANY, LTD. (JP) 1990-12-25 US disclosed
EP-0333498-A2 Process for preparation of a gelled polyester for toner MITSUBISHI RAYON CO., LTD. (JP) 1989-09-20 EP disclosed