SCHEMBL8763187

SCHEMBL8763187

CC=CC(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.52
ESR2 Q92731 11/20 0.52
CYP3A4 P08684 5/20 0.52
LMNA P02545 3/20 0.52
HSD17B10 Q99714 3/20 0.52
TYR P14679 2/20 0.52
HPGD P15428 2/20 0.52
AR P10275 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
ALDH1A1 P00352 3/20 0.45
SHBG P04278 1/20 0.43
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25423816 0.82 ESR1 (0.52) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL4453506 0.81 ESR1 (0.56) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL14255700 0.79 ESR1 (0.54) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL8943820 0.77 ESR1 (0.46) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL600734 0.77 ESR1 (0.46) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL13275922 0.77 ESR1 (0.47) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL21701236 0.76 ESR1 (0.56) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL8611387 0.76 MAPK1 (0.42) ESR1ESR2CYP3A4TSHRALDH1A1
Bisphenol A SCHEMBL1518029 0.74 ESR1 (0.76) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL601524 0.74 ESR1 (0.43) ESR1ESR2CYP3A4LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993208-B2 Foil transferring method and toner for forming foil transferring layer KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2015-03-31 US disclosed
US-20120264045-A1 FOIL TRANSFERRING METHOD AND TONER FOR FORMING FOIL TRANSFERRING LAYER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC,. (JP) 2012-10-18 US disclosed
EP-0333498-B1 Process for preparation of a gelled polyester for toner MITSUBISHI RAYON CO (JP) 1997-07-16 EP disclosed
US-4980448-A OFFSET AND BLOCKING RESISTANCE; SELF-CHARGING; SHARP COPIED IMAGES MITSUBISHI RAYON COMPANY, LTD. (JP) 1990-12-25 US disclosed
EP-0333498-A2 Process for preparation of a gelled polyester for toner MITSUBISHI RAYON CO., LTD. (JP) 1989-09-20 EP disclosed