SCHEMBL8943820

SCHEMBL8943820

CC=CC(O)(O)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.46
ESR2 Q92731 10/20 0.46
CYP3A4 P08684 4/20 0.46
LMNA P02545 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TYR P14679 2/20 0.46
HPGD P15428 2/20 0.46
AR P10275 1/20 0.46
TSHR P16473 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
ESRRG P62508 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
KMT2A Q03164 2/20 0.39
HIF1A Q16665 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763187 0.77 ESR1 (0.52) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL25423816 0.77 ESR1 (0.52) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL9302742 0.73 ESR1 (0.48) ESR1ESR2CYP3A4LMNAHSD17B10
Bisphenol A SCHEMBL1518029 0.70 ESR1 (0.76) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL12970245 0.70 ESR1 (0.48) ESR1ESR2CYP3A4LMNAHSD17B10
Hydroquinone SCHEMBL4670570 0.68 HSD17B10 (0.57) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL548276 0.67 ESR1 (0.65) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL20673138 0.67 ESR1 (0.65) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL13917765 0.67 ESR1 (0.65) ESR1ESR2CYP3A4LMNAHSD17B10
SCHEMBL6036607 0.67 ESR1 (0.65) ESR1ESR2CYP3A4LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516342-A ANTIDEPOSIT AGENTS FOR AUTOMOBILES USING NONIONIC SURFACTANTS FOR ADDITION TO GASOLINE CHEVRON CHEMICAL COMPANY (US) 1996-05-14 US disclosed
US-5366517-A Fuel additive compositions containing poly(oxyalkylene) hydroxyaromatic ethers and poly(oxyalkylene) amines CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1994-11-22 US disclosed