SCHEMBL8763269

SCHEMBL8763269

O=C=NCc1ccccc1Cc1ccccc1CN=C=O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
HSPA5 P11021 1/20 0.36
CYP3A4 P08684 3/20 0.31
TSHR P16473 1/20 0.31
TRPA1 O75762 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MIF P14174 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127043 0.93 GABRA1 (0.41) GABRA1GABRB2CYP3A4TSHRTRPA1
SCHEMBL29364508 0.93 GABRA1 (0.41) GABRA1GABRB2CYP3A4TSHRTRPA1
Water SCHEMBL5172983 0.91 GABRA1 (0.40) GABRA1GABRB2CYP3A4TRPA1ALDH1A1
SCHEMBL28225610 0.91 GABRA1 (0.40) GABRA1GABRB2CYP3A4TRPA1ALDH1A1
Benzene SCHEMBL28107745 0.91 GABRA1 (0.40) GABRA1GABRB2CYP3A4TRPA1ALDH1A1
SCHEMBL27885870 0.87 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL28454008 0.86 GABRA1 (0.38) GABRA1GABRB2CYP3A4TRPA1ALDH1A1
Propane SCHEMBL28338597 0.86 GABRA1 (0.47) GABRA1GABRB2CYP3A4TSHRTRPA1
SCHEMBL5945281 0.86 GABRA1 (0.38) GABRA1GABRB2CYP3A4TRPA1ALDH1A1
SCHEMBL1457269 0.84 GABRA1 (0.50) GABRA1GABRB2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-4388245-A OF LOW VISCOSITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-06-14 US disclosed