SCHEMBL8763286

SCHEMBL8763286

CC(CCCC(C)N=C=S)N=C=S

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.59
TRPV1 Q8NER1 2/20 0.59
MIF P14174 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6892191 0.93 TRPA1 (0.52) TRPA1TRPV1MIF
SCHEMBL30350978 0.88 TRPA1 (0.65) TRPA1TRPV1MIF
SCHEMBL11422618 0.87
SCHEMBL6154825 0.85 TRPA1 (0.56) TRPA1TRPV1
SCHEMBL7979579 0.84 TRPA1 (0.54) TRPA1TRPV1
SCHEMBL8739301 0.84 TRPA1 (0.54) TRPA1TRPV1
SCHEMBL11510043 0.82 TRPA1 (0.52) TRPA1TRPV1MIF
SCHEMBL14268357 0.82 TRPA1 (0.46) TRPA1TRPV1
SCHEMBL14268359 0.82 TRPA1 (0.46) TRPA1TRPV1
SCHEMBL9282879 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed