Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28262918 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL28950119 | 0.85 | TSHR (0.64) | TSHRTHRBALDH1A1 | |
| SCHEMBL1574109 | 0.85 | TSHR (0.59) | TSHRTHRBALDH1A1 | |
| SCHEMBL19519756 | 0.84 | TSHR (0.68) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4373928 | 0.84 | TSHR (0.57) | TSHRTHRBALDH1A1 | |
| SCHEMBL94906 | 0.81 | TSHR (0.68) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL21560979 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL20029770 | 0.80 | TSHR (0.62) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL19998240 | 0.79 | TSHR (0.65) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL3407482 | 0.78 | TSHR (0.55) | TSHRTHRBALDH1A1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783589-A1 | TRANSPORTABILITY IMPROVER FOR PULVERIZED COAL | Kao Corporation (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010093-A1 | TRANSPORTABILITY IMPROVER FOR PULVERIZED COAL | KAO CORPORATION (JP) | 1996-04-04 | — | — | WO | disclosed |
| US-4663061-A | Metal-working oil composition | KAO CORPORATION (JP) | 1987-05-05 | — | — | US | disclosed |