Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574109 | 0.98 | TSHR (0.59) | TSHRTHRBALDH1A1GABRR1LMNA | |
| SCHEMBL94906 | 0.86 | TSHR (0.68) | TSHRTHRBALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL5333198 | 0.85 | TSHR (0.53) | TSHRTHRBALDH1A1GABRR1 | |
| SCHEMBL8763307 | 0.84 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL19998240 | 0.84 | TSHR (0.65) | TSHRTHRBALDH1A1LMNAHTT | |
| Benzoic Acid SCHEMBL11145394 | 0.82 | POLB (0.46) | TSHRALDH1A1LMNAHTTALOX15 | |
| Hydrochloric Acid SCHEMBL534137 | 0.81 | TSHR (0.57) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL3078233 | 0.81 | TSHR (0.57) | TSHRTHRBALDH1A1LMNAHTT | |
| SCHEMBL203733 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1LMNAHTT | |
| SCHEMBL3412123 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810967-A1 | FLUORINE-CONTAINING COPOLYMER, METHOD FOR PRODUCING SAME, AND WATER-/OIL-REPELLANT AGENT COMPOSITION | Asahi Glass Company, Limited (JP) | 2014-12-10 | — | — | EP | disclosed |
| EP-2810966-A1 | FLUORINE-CONTAINING COPOLYMER AND METHOD FOR PRODUCING SAME, AND WATER REPELLENT/OIL REPELLENT AGENT COMPOSITION | Asahi Glass Company, Limited (JP) | 2014-12-10 | — | — | EP | disclosed |
| US-20140343206-A1 | FLUORINATED COPOLYMER AND PROCESS FOR ITS PRODUCTION, AND WATER/OIL REPELLENT COMPOSITION | ASAHI GLASS COMPANY, LIMITED (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20140343207-A1 | FLUORINATED COPOLYMER AND PROCESS FOR ITS PRODUCTION, AND WATER/OIL REPELLENT COMPOSITION | ASAHI GLASS COMPANY, LIMITED (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20140171593-A1 | FLUORINATED BLOCK COPOLYMER AND PROCESS FOR ITS PRODUCTION, AND SURFACE TREATMENT AGENT | ASAHI GLASS COMPANY, LIMITED (JP) | 2014-06-19 | — | — | US | disclosed |
| US-20090087761-A1 | Resin composition for electrophotographic photoconductor and electrophotographic photoconductor using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-2042931-A1 | Resin composition for electrophotographic photoconductor and electrophotographic photoconductor using the same | Mitsubishi Gas Chemical Company, Inc. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2007013637-A1 | METHOD FOR FORMING GRAFT POLYMER PATTERN AND METHOD FOR FORMING ELECTRICALLY CONDUCTIVE PATTERN | FUJIFILM CORPORATION (JP) | 2007-02-01 | — | — | WO | disclosed |