Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10788742 | 0.98 | ALDH1A1 (0.33) | ALDH1A1ATML3MBTL1KDM4EMEN1 | |
| SCHEMBL11095009 | 0.84 | ALDH1A1 (0.34) | ALDH1A1ATML3MBTL1KDM4EKMT2A | |
| SCHEMBL11095006 | 0.82 | ALDH1A1 (0.33) | ALDH1A1ATML3MBTL1KMT2AHPGD | |
| SCHEMBL8761691 | 0.82 | ALDH1A1 (0.37) | ALDH1A1ATML3MBTL1KMT2AHPGD | |
| SCHEMBL27583635 | 0.78 | KMT2A (0.41) | ALDH1A1ATML3MBTL1KDM4EMEN1 | |
| SCHEMBL5847084 | 0.76 | ALDH1A1 (0.34) | ALDH1A1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL9531309 | 0.72 | ALDH1A1 (0.37) | ALDH1A1ATML3MBTL1KDM4EKMT2A | |
| SCHEMBL28095620 | 0.71 | ALDH1A1 (0.37) | ALDH1A1ATML3MBTL1KDM4EKMT2A | |
| SCHEMBL1626189 | 0.68 | CYP1A2 (0.50) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL5518789 | 0.68 | HSD17B10 (0.35) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560365-B1 | Cephalosporin derivative | MEIJI SEIKA KAISHA (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0590681-B1 | A process for the preparation of aminothiadiazolylacetyl halide derivatives | EISAI KAGAKU KK (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5607927-A | ANTIBIOTIC BACTERICIDE | MEIJI SEIKA KAISHA, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5464829-A | Cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5428173-A | Halogenating corresponding aminothiadiazolylacetic acid | EISAI CHEMICAL CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0605836-A1 | Cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |
| EP-0590681-A2 | A process for the preparation of aminothiadiazolylacetyl halide derivatives | EISAI CHEMICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0560365-A1 | Cephalosporin derivative | MEIJI SEIKA KAISHA LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4626535-A | Cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-02 | — | — | US | disclosed |