Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374420 | 0.87 | CASR (0.67) | CASRMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL711162 | 0.84 | SMN1; SMN2 (0.58) | CASRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL27484718 | 0.83 | POLB (0.55) | MEN1KMT2ASMN1; SMN2CYP3A4MAPT | |
| SCHEMBL11582892 | 0.81 | MEN1 (0.70) | CASRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL26496477 | 0.81 | MEN1 (0.75) | CASRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3828194 | 0.80 | L3MBTL1 (0.57) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL28837773 | 0.80 | CYP3A4 (0.63) | CASRMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL14574199 | 0.80 | MEN1 (0.56) | CASRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11632076 | 0.79 | NAMPT (0.60) | CASRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11632613 | 0.79 | CASR (0.55) | CASRMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1164225-A | Iodinated X-ray-contrast media | NYCOMED IMAGING AS (NO) | 1997-11-05 | — | — | CN | disclosed |
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |