Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8763902

COC(=O)[C@H](CCSC)NC(=O)CN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.49

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.49
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TAS1R3 Q7RTX0 2/20 0.44
TAS1R1 Q7RTX1 2/20 0.44
USP2 O75604 1/20 0.44
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
GAA P10253 2/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CASP1 P29466 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749748 0.90 CYP2C9 (0.57) CYP2C9ALDH1A1TSHRHTTL3MBTL1
SCHEMBL7749751 0.90 CYP2C9 (0.57) CYP2C9ALDH1A1TSHRHTTL3MBTL1
Hydrochloric Acid SCHEMBL8368672 0.89 CYP2C9 (0.56) CYP2C9ALDH1A1TSHRHTTL3MBTL1
Hydrochloric Acid SCHEMBL8368674 0.89 CYP2C9 (0.56) CYP2C9ALDH1A1TSHRHTTL3MBTL1
Trifluoroacetic Acid SCHEMBL8763021 0.87 SMN1; SMN2 (0.47) ALDH1A1TSHRUSP2CA1CA2
Triaziquone SCHEMBL8763899 0.81 TSHR (0.37) CYP2C9ALDH1A1TSHRHTTL3MBTL1
Trifluoroacetic Acid SCHEMBL11291163 0.79 FNTA (0.42) CYP2C9ALDH1A1TSHRHTTL3MBTL1
Trifluoroacetic Acid SCHEMBL11291166 0.79 FNTA (0.42) CYP2C9ALDH1A1TSHRHTTL3MBTL1
SCHEMBL28046501 0.78 CYP2C9 (0.57) CYP2C9ALDH1A1TSHRHTTL3MBTL1
SCHEMBL28046500 0.78 CYP2C9 (0.57) CYP2C9ALDH1A1TSHRHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0783517-A2 THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP disclosed