SCHEMBL28046501

SCHEMBL28046501

COC(=O)C(CCSC)NC(=O)CC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.57
ALDH1A1 P00352 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
TAS1R3 Q7RTX0 2/20 0.50
TAS1R1 Q7RTX1 2/20 0.50
USP2 O75604 1/20 0.50
HTT P42858 1/20 0.48
HPGD P15428 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
CASP1 P29466 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28046500 1.00 CYP2C9 (0.57) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL7749748 0.87 CYP2C9 (0.57) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL7749751 0.87 CYP2C9 (0.57) CYP2C9ALDH1A1GAATSHRL3MBTL1
Hydrochloric Acid SCHEMBL8368674 0.85 CYP2C9 (0.56) CYP2C9ALDH1A1GAATSHRL3MBTL1
Hydrochloric Acid SCHEMBL8368672 0.85 CYP2C9 (0.56) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL11940463 0.85 CYP2C9 (0.58) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL25724298 0.85 CYP2C9 (0.62) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL11205882 0.84 ALDH1A1 (0.56) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL111170 0.84 ALDH1A1 (0.56) CYP2C9ALDH1A1GAATSHRL3MBTL1
SCHEMBL111169 0.84 ALDH1A1 (0.56) CYP2C9ALDH1A1GAATSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778188-A Preparation method of alternaria tenuifolia keto acid and derivatives thereof 安徽农业大学 2021-05-11 CN disclosed
CN-105145577-A Application of sulfur derivatives of pyrrolinones UNIV NANJING AGRICULTURAL 2015-12-16 CN disclosed