Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828391 | 0.77 | TSHR (0.36) | TSHRTHRBLMNA | |
| SCHEMBL828128 | 0.74 | TSHR (0.32) | TSHRTHRB | |
| SCHEMBL8764126 | 0.73 | TSHR (0.42) | TSHRTHRBLMNAAPAF1HSP90AA1 | |
| SCHEMBL7036618 | 0.72 | TSHR (0.47) | TSHRTHRBLMNA | |
| SCHEMBL4959288 | 0.72 | TSHR (0.47) | TSHRTHRBLMNA | |
| SCHEMBL9859881 | 0.72 | TSHR (0.47) | TSHRTHRBLMNA | |
| SCHEMBL11024773 | 0.72 | TSHR (0.47) | TSHRTHRBLMNA | |
| SCHEMBL19356773 | 0.70 | TSHR (0.44) | TSHRTHRBLMNA | |
| SCHEMBL18528250 | 0.70 | TSHR (0.44) | TSHRTHRBLMNA | |
| SCHEMBL610798 | 0.70 | TSHR (0.44) | TSHRTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349195-B1 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC (US) | 1997-05-21 | — | — | EP | disclosed |
| US-5444135-A | Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously | EXXON CHEMICAL PATENTS INC. (US) | 1995-08-22 | — | — | US | disclosed |
| US-5336745-A | Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators | EXXON CHEMICAL PATENTS INC. (US) | 1994-08-09 | — | — | US | disclosed |
| US-5032653-A | Catalysts | EXXON CHEMICAL PATENTS, INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0349195-A2 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC. (US) | 1990-01-03 | — | — | EP | disclosed |