SCHEMBL4959288

SCHEMBL4959288

CCCCCC[Si](CCCCCC)(CCCCCC)O[Si](CCCCCC)(CCCCCC)CCCCCC

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
DNM1 Q05193 7/20 0.36
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9859881 1.00 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7036618 1.00 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL11024773 1.00 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL18528250 0.97 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6017704 0.97 TSHR (0.41) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5940456 0.88 TSHR (0.38) TSHRTHRBALDH1A1LMNA
SCHEMBL23781420 0.87 TSHR (0.40) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8409898 0.85 DNM1 (0.48) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL17088158 0.82 TSHR (0.33) TSHRTHRBLMNA
SCHEMBL15847432 0.80 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424147-A1 PHTHALOCYANINE-LOADED MICELLES FOR THE DIRECT VISUALIZATION OF TUMORS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-12-26 US claimed
WO-2023060147-A1 PHTHALOCYANINE-LOADED MICELLES FOR THE DIRECT VISUALIZATION OF TUMORS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-04-13 WO claimed
CN-119367521-A Multifunctional self-bionic nano vaccine for treating breast cancer and preparation method and application thereof 广州医科大学附属第二医院 2025-01-28 CN disclosed
CN-119326731-A Preparation of hypoxia-responsive albumin supermolecule nano drug delivery system and application of hypoxia-responsive albumin supermolecule nano drug delivery system in treatment of hypoxia tumors 中山大学 2025-01-21 CN disclosed
US-20240424147-A1 PHTHALOCYANINE-LOADED MICELLES FOR THE DIRECT VISUALIZATION OF TUMORS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-12-26 US disclosed
US-11740238-B2 Compositions and methods of detecting a substance of interest PIONEER HI-BRED INTERNATIONAL, INC. 2023-08-29 US disclosed
CN-108695356-B Image pickup apparatus 松下知识产权经营株式会社 2023-08-01 CN disclosed
WO-2023060147-A1 PHTHALOCYANINE-LOADED MICELLES FOR THE DIRECT VISUALIZATION OF TUMORS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-04-13 WO disclosed
WO-2023032559-A1 PHOTOELECTRIC CONVERSION MATERIAL AND LIGHT DETECTION METHOD パナソニックIPマネジメント株式会社 2023-03-09 WO disclosed
EP-3140872-A1 CRYSTALLIZATION OF ADDITIVES AT P/N JUNCTIONS OF BULK-HETEROJUNCTION PHOTOACTIVE LAYERS SABIC Global Technologies B.V. (NL) 2017-03-15 EP disclosed
US-20170054077-A1 CRYSTALLIZATION OF ADDITIVES AT P/N JUNCTIONS OF BULK-HETEROJUNCTION PHOTOACTIVE LAYERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-23 US disclosed
US-6964844-B1 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2005-11-15 US disclosed
US-20030065117-A1 Modified silicone compound, process of producing the same, and cured object obtained therefrom NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2003-04-03 US disclosed
US-6251687-B1 PARTICLE CONTAINING ENERGY DONOR AND ENERGY ACCEPTOR BIOSITE DIAGNOSTICS, INC. 2001-06-26 US disclosed
US-5760251-A Taxol process and compounds SEPRACOR, INC. (US) 1998-06-02 US disclosed
WO-1997007110-A1 PROCESS FOR PRODUCING TAXOL DERIVATIVES AND INTERMEDIATES THEREFOR SEPRACOR, INC. (US) 1997-02-27 WO disclosed
EP-0068479-B1 PROCESS FOR MAKING ALCOHOLS UNION CARBIDE CORPORATION (US) 1984-10-24 EP disclosed
EP-0068479-A1 Process for making alcohols UNION CARBIDE CORPORATION (US) 1983-01-05 EP disclosed
US-4362820-A FROM HYDROGEN AND CARBON MONOXIDE, COBALT COMPOUND, ORGANOSILICON COMPOUND UNION CARBIDE CORPORATION (US) 1982-12-07 US disclosed
US-4345103-A SYNTHESIS GAS, ALCOHOL FORMATION UNION CARBIDE CORPORATION (US) 1982-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065117-A1 Modified silicone compound, process of producing the same, and cured object obtained therefrom ORMDL3, SGMS1, HEATR1 TSHR 2675/4885THRB 2591/4885DNM1 4579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.