Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.59 |
| ▸ | FCER2 | P06734 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 14/20 | 0.57 |
| ▸ | MMP3 | P08254 | 7/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | MMP7 | P09237 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669159 | 0.90 | MMP1 (0.61) | MMP1FCER2MMP2MMP3MMP9 | |
| SCHEMBL30011374 | 0.87 | MME (0.62) | MMP2 | |
| SCHEMBL29892434 | 0.87 | MME (0.62) | MMP2 | |
| SCHEMBL31025582 | 0.87 | MME (0.62) | MMP2 | |
| SCHEMBL30010588 | 0.87 | MME (0.62) | MMP2 | |
| SCHEMBL31025651 | 0.87 | MME (0.62) | MMP2 | |
| SCHEMBL14958103 | 0.87 | MME (0.66) | MMP2 | |
| SCHEMBL14787211 | 0.87 | MME (0.66) | MMP2 | |
| SCHEMBL16421158 | 0.87 | MME (0.66) | MMP2 | |
| SCHEMBL29937707 | 0.87 | MME (0.66) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |