Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800203 | 1.00 | CASP1 (0.64) | CASP1CASP3 | |
| SCHEMBL13139829 | 0.89 | CASP1 (0.50) | CASP1CASP3 | |
| SCHEMBL646855 | 0.88 | CASP1 (0.50) | CASP1CASP3 | |
| SCHEMBL646040 | 0.82 | CASP1 (0.65) | CASP1 | |
| SCHEMBL646856 | 0.80 | CASP1 (0.48) | CASP1 | |
| SCHEMBL646776 | 0.80 | SMN1; SMN2 (0.44) | CASP1 | |
| SCHEMBL6195579 | 0.76 | CASP1 (0.73) | CASP1 | |
| SCHEMBL12522514 | 0.75 | CASP1 (0.63) | CASP1 | |
| SCHEMBL949463 | 0.75 | CASP1 (0.63) | CASP1 | |
| SCHEMBL7251515 | 0.75 | SMN1; SMN2 (0.42) | CASP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784628-A1 | INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | Vertex Pharmaceuticals Incorporated (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1995035308-A1 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-12-28 | — | — | WO | disclosed |