Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736693 | 0.86 | ALOX15 (0.47) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL16736925 | 0.82 | MCL1 (0.47) | MCL1ESR1ESR2SLC22A12ALOX15 | |
| SCHEMBL14298135 | 0.82 | BACE1 (0.40) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL11038842 | 0.82 | ESR1 (0.48) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL6040093 | 0.79 | ALOX15 (0.56) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL1760478 | 0.79 | ALOX15 (0.54) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL16736819 | 0.79 | HMGCR (0.44) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL69600 | 0.79 | TYR (0.53) | ESR1ALOX15KDM4EMAPTMAPK1 | |
| SCHEMBL18209542 | 0.77 | MCL1 (0.43) | MCL1ESR1ESR2ALOX15KDM4E | |
| SCHEMBL4462620 | 0.77 | HMGCR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623339-B1 | Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation | OREAL (FR) | 1997-07-23 | — | — | EP | claimed |