SCHEMBL8764494

SCHEMBL8764494

O=C(O)CCCCc1ccc(O)cc1O

nearest known ligand 0.77

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.59
MEN1 O00255 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
ALOX5 P09917 1/20 0.59
MAPT P10636 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
HTT P42858 1/20 0.59
KMT2A Q03164 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
F13A1 P00488 3/20 0.55
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764373 0.96 TYR (0.63) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL6582394 0.87 F13A1 (0.56) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL490491 0.87 POLB (0.67) TYRPOLB
SCHEMBL29998634 0.87 POLB (0.67) TYRPOLB
SCHEMBL28799269 0.86 CHRNA7 (0.55) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL4148828 0.86 F13A1 (0.59) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL7855812 0.86 TYR (0.64) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL2381980 0.86 F13A1 (0.59) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL3838231 0.86 F13A1 (0.59) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL3840098 0.86 F13A1 (0.59) TYRMEN1TP53CYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed