Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 3/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148828 | 1.00 | F13A1 (0.59) | F13A1EGFRLCKMAPTRXFP1 | |
| SCHEMBL3840098 | 1.00 | F13A1 (0.59) | F13A1EGFRLCKMAPTRXFP1 | |
| SCHEMBL3838231 | 1.00 | F13A1 (0.59) | F13A1EGFRLCKMAPTRXFP1 | |
| SCHEMBL6582394 | 0.98 | F13A1 (0.56) | F13A1EGFRLCKMAPTRXFP1 | |
| SCHEMBL3842422 | 0.93 | EGFR (0.54) | F13A1EGFRLCKTP53CYP3A4 | |
| SCHEMBL3835233 | 0.90 | F13A1 (0.49) | F13A1EGFRLCKMAPTRXFP1 | |
| SCHEMBL13065628 | 0.87 | TYR (0.57) | EGFRLCKMAPTTP53CYP3A4 | |
| SCHEMBL10602853 | 0.86 | TP53 (0.47) | F13A1EGFRLCKMAPTTP53 | |
| SCHEMBL7785687 | 0.86 | EGFR (0.47) | F13A1EGFRLCKMAPTTP53 | |
| SCHEMBL8764494 | 0.86 | TYR (0.59) | F13A1MAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449518-A | Bleaching, decoloring skin | L'OREAL (FR) | 1995-09-12 | — | — | US | claimed |
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| US-8505730-B2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | JR CHEM, LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8466311-B2 | Neuroprotective compositions and methods | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466311-B2 | Neuroprotective compositions and methods | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120312717-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | JR CHEM, LLC (US) | 2012-12-13 | — | — | US | disclosed |
| US-20120296112-A1 | Neuroprotective Compositions and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-22 | — | — | US | disclosed |
| US-20120296112-A1 | Neuroprotective Compositions and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-22 | — | — | US | disclosed |
| US-8273791-B2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | JR CHEM, LLC (US) | 2012-09-25 | — | — | US | disclosed |
| US-8022246-B2 | Neuroprotective compositions and methods | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2011-09-20 | — | — | US | disclosed |
| US-8022246-B2 | Neuroprotective compositions and methods | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2011-09-20 | — | — | US | disclosed |
| US-20010036446-A1 | Composition based on N-cholesteryloxycarbonyl-4-para-aminophenol and hydroquinone or one of its derivatives | L'OREAL (FR) | 2001-11-01 | — | — | US | disclosed |
| US-5667792-A | CARBOXY DERIVATIVES OF HYDROQUINONE AS BLEACHES FOR SKIN | L'OREAL (FR) | 1997-09-16 | — | — | US | disclosed |
| US-5637756-A | TREATMENT OF SKIN DISORDERS, BLEACHING OF PIGMENTED SPOTS, COSMETICS | L'OREAL (FR) | 1997-06-10 | — | — | US | disclosed |
| US-5587173-A | Utilization of derivatives of 2,5 dihydroxyphenyl-carboxylic acid amides and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action | L'OREAL (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5585105-A | Utilization of derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action | L'OREAL (FR) | 1996-12-17 | — | — | US | disclosed |
| US-5449518-A | Bleaching, decoloring skin | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5190689-A | Polymer materials having liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0220463-B1 | POLYMER MATERIALS PRESENTING A LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0220463-A2 | Polymer materials presenting a liquid crystal phase | MERCK PATENT GmbH (DE) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120296112-A1 | Neuroprotective Compositions and Methods | KEAP1, NFE2L2, NQO1 | F13A1 4703/4885EGFR 3947/4885LCK 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.