Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.58 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764536 | 1.00 | GRIK1 (0.58) | GRIK1EP300GRIK2TERTPTPN1 | |
| Fluoride SCHEMBL27740263 | 0.86 | GRIK1 (0.55) | GRIK1EP300GRIK2TERTPTPN1 | |
| SCHEMBL13013816 | 0.86 | EP300 (0.47) | GRIK1EP300TERTPTPN1PPARG | |
| SCHEMBL11546520 | 0.85 | GRIK1 (0.65) | GRIK1EP300GRIK2CYP1A2TDP1 | |
| SCHEMBL11546522 | 0.85 | GRIK1 (0.65) | GRIK1EP300GRIK2CYP1A2TDP1 | |
| SCHEMBL27147872 | 0.84 | EP300 (0.46) | GRIK1EP300MAPTBLMHSD17B10 | |
| SCHEMBL28621418 | 0.81 | GRIK1 (0.54) | GRIK1EP300GRIK2MAPTBLM | |
| SCHEMBL28626388 | 0.81 | GRIK1 (0.54) | GRIK1EP300GRIK2MAPTBLM | |
| SCHEMBL28621414 | 0.81 | GRIK1 (0.54) | GRIK1EP300GRIK2MAPTBLM | |
| SCHEMBL27636120 | 0.81 | GRIK1 (0.54) | GRIK1EP300GRIK2MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621257-B1 | Doubly branched compounds and methods of making them | INST FRANCAIS DU PETROLE (FR) | 1997-07-30 | — | — | EP | disclosed |
| US-5434282-A | Alkylation | INSTITUT FRANCAIS DU PETROLE (FR) | 1995-07-18 | — | — | US | disclosed |
| EP-0621257-A1 | Doubly branched compounds and methods of making them | INSTITUT FRANCAIS DU PETROLE (FR) | 1994-10-26 | — | — | EP | disclosed |