Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL5050874 | 0.92 | PLA2G4B (0.68) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL28279260 | 0.89 | PPARA (0.71) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL8133488 | 0.89 | PPARA (0.71) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL2233264 | 0.89 | PPARA (0.71) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL2255415 | 0.89 | PPARA (0.71) | HTTPLA2G4BPPARATP53TSHR | |
| Terephthalic Acid SCHEMBL23910546 | 0.89 | HTT (0.55) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL11589042 | 0.89 | PPARA (0.71) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL2219999 | 0.88 | HTT (0.49) | HTTPLA2G4BPPARATP53TSHR | |
| SCHEMBL2230125 | 0.87 | PPARA (0.73) | HTTPLA2G4BPPARATP53TSHR | |
| Terephthalic Acid SCHEMBL28904546 | 0.86 | TP53 (0.58) | HTTPLA2G4BPPARATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774964-A1 | CONTROLLED LOCAL DELIVERY OF CHEMOTHERAPEUTIC AGENTS FOR TREATING SOLID TUMORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996003984-A1 | CONTROLLED LOCAL DELIVERY OF CHEMOTHERAPEUTIC AGENTS FOR TREATING SOLID TUMORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-02-15 | — | — | WO | disclosed |