Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765009 | 0.84 | PRSS1 (0.47) | PRSS1TSHR | |
| SCHEMBL3026889 | 0.81 | PRSS1 (0.45) | KCNA3PRSS1TSHR | |
| SCHEMBL7297045 | 0.81 | TSHR (0.62) | TSHRKMT2A | |
| SCHEMBL9717879 | 0.80 | TSHR (0.65) | TSHRKMT2A | |
| SCHEMBL8766568 | 0.80 | TSHR (0.65) | TSHRKMT2A | |
| SCHEMBL2089702 | 0.80 | TSHR (0.65) | TSHRKMT2A | |
| SCHEMBL1665036 | 0.80 | TSHR (0.65) | TSHRKMT2A | |
| SCHEMBL5961833 | 0.80 | KCNA3 (0.48) | KCNA3PRSS1TSHR | |
| SCHEMBL1805409 | 0.79 | TSHR (0.54) | TSHRKMT2A | |
| SCHEMBL8764935 | 0.78 | CHRNB2 (0.57) | PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |