Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23020157 | 0.81 | L3MBTL1 (0.42) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL8582607 | 0.78 | L3MBTL1 (0.43) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL510210 | 0.78 | L3MBTL1 (0.43) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL6293250 | 0.78 | L3MBTL1 (0.43) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL25629718 | 0.78 | L3MBTL1 (0.40) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL13073704 | 0.77 | GRM5 (0.43) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL19865639 | 0.77 | L3MBTL1 (0.42) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL11373743 | 0.77 | L3MBTL1 (0.42) | L3MBTL1TDP1KAT2BNPC1CASP3 | |
| SCHEMBL510211 | 0.77 | CYP2C9 (0.43) | L3MBTL1TDP1KAT2BPDE4APDE4B | |
| SCHEMBL24440199 | 0.77 | L3MBTL1 (0.42) | L3MBTL1TDP1KAT2BNPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522674-B | Novel compounds, pharmaceutically acceptable salts as vanilloid receptor antagonist and pharmaceutical composition comprising the compounds | AMOREPACIFIC CORP | 2013-08-21 | — | — | CN | disclosed |
| CN-101522674-A | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist | AMOREPACIFIC CORP (KR) | 2009-09-02 | — | — | CN | disclosed |
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |