SCHEMBL8765008

SCHEMBL8765008

CCOc1ccc([SiH](C)[SiH2][SiH3])cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.54
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
LTA4H P09960 2/20 0.42
PLA2G4B P0C869 1/20 0.42
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PARP10 Q53GL7 1/20 0.39
RELA Q04206 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
ADRA2A P08913 2/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764964 0.82 NQO1 (0.56) NQO1TSHRTDP1LTA4HPLA2G4B
SCHEMBL6707973 0.77 NQO1 (0.67) NQO1TSHRTDP1LTA4HPLA2G4B
SCHEMBL15878867 0.74 NQO1 (0.70) NQO1TSHRTDP1LTA4HPLA2G4B
SCHEMBL9617383 0.74 NQO1 (0.61) NQO1TSHRTDP1LTA4HPLA2G4B
1,4-Diethoxybenzene SCHEMBL28186701 0.73 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL124015 0.73 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL8764967 0.71 NQO1 (0.64) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL3298993 0.71 NQO1 (0.64) NQO1TSHRTDP1LTA4HPLA2G4B
1,4-Diethoxybenzene SCHEMBL11794798 0.71 NQO1 (0.93) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL8765665 0.71 NQO1 (0.56) NQO1TSHRTDP1LTA4HPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed