Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15878867 | 0.83 | NQO1 (0.70) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL9617383 | 0.82 | NQO1 (0.61) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.82 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.82 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL3298993 | 0.79 | NQO1 (0.64) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL11794798 | 0.79 | NQO1 (0.93) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL8653802 | 0.77 | NQO1 (0.61) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL6055007 | 0.77 | NQO1 (0.37) | NQO1TSHRTDP1SMN1; SMN2CA12 | |
| SCHEMBL8765008 | 0.77 | NQO1 (0.54) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL27616183 | 0.76 | NQO1 (0.88) | NQO1TSHRTDP1LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139785-A | Synergistic mixture of a silane-containing compound and a pesticides; insecticides, miticides and nematocides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-18 | — | — | US | claimed |
| JP-4288087-A | — | — | None | — | — | JP | disclosed |
| US-8778837-B2 | Use of active substance combinations for controlling animal pests | BAYER CROPSCIENCE AG (DE) | 2014-07-15 | — | — | US | disclosed |
| US-20140080820-A1 | FUNGICIDAL AGENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20040127363-A1 | Pesticidal compositions containing silicon compounds | KIDRON AGROCHEM LTD. (IL) | 2004-07-01 | — | — | US | disclosed |
| EP-1370142-A2 | PESTICIDAL COMPOSITIONS CONTAINING SILICON COMPOUNDS | Kidron Agrochem Ltd (IL) | 2003-12-17 | — | — | EP | disclosed |
| WO-2001067863-A2 | PESTICIDAL COMPOSITIONS CONTAINING SILICON COMPOUNDS | KIDRON AGROCHEM LTD. (IL) | 2001-09-20 | — | — | WO | disclosed |
| CN-1044661-C | Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives | HOECHST AG (DE) | 1999-08-18 | — | — | CN | disclosed |
| EP-0543238-B1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| CN-1032005-C | Novel silane derivatives, formulations containing them and their use as pesticides | HOECHST AG (DE) | 1996-06-12 | — | — | CN | disclosed |
| EP-0479244-A1 | Process for the preparation of 4-ethoxyphenyl-3-arylpropyl-dimethyl silanes | Hoechst Schering AgrEvo GmbH (DE) | 1992-04-08 | — | — | EP | disclosed |
| EP-0468373-A1 | Process for the preparation of aryl-alkyl-methylsilanes | Hoechst Schering AgrEvo GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |
| CN-1050878-A | Novel silane derivs contains the preparation of this derivative and as the application of agricultural chemicals | HOECHST AG (DE) | 1991-04-24 | — | — | CN | disclosed |
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0224024-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| US-4920212-A | Process for the preparation of (aryl)-(dimethyl)-(3-(4-fluoro-3-aryloxyphenyl)propyl)silanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0308788-A2 | Process for the preparation of (aryl)-(dimethyl)-(3-(4-fluoro-3-aryloxyphenyl)propyl) silanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-29 | — | — | EP | disclosed |
| CN-86107292-A | Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides | — | 1987-07-29 | — | — | CN | disclosed |
| EP-0224024-A1 | Silane derivatives, process for their preparation, agents containing them and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080820-A1 | FUNGICIDAL AGENT COMBINATIONS | DDT, COXFA4L2, CYP4X1 | NQO1 240/4885TSHR 4270/4885TDP1 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.