Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9868216 | 0.98 | MAPT (0.57) | MAPTTP53SMN1; SMN2ALDH1A1FPR3 | |
| SCHEMBL22170168 | 0.83 | ALDH1A1 (0.70) | TP53SMN1; SMN2ALDH1A1FPR3FPR2 | |
| SCHEMBL13661591 | 0.83 | MAPT (0.70) | MAPTSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL13584907 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL1768711 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL24703317 | 0.80 | SMN1; SMN2 (0.44) | MAPTTP53SMN1; SMN2ALDH1A1FPR3 | |
| SCHEMBL4578493 | 0.80 | MAPT (0.66) | MAPTTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4578490 | 0.80 | MAPT (0.66) | MAPTTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL24703507 | 0.79 | POLB (0.43) | MAPTTP53SMN1; SMN2ALDH1A1FPR3 | |
| SCHEMBL9579390 | 0.78 | MAPT (0.61) | MAPTTP53SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420116-B1 | Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis | MERRELL PHARMA INC (US) | 1997-07-30 | — | — | EP | claimed |