SCHEMBL8765463

SCHEMBL8765463

[O]c1cnccc1C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.33
GAA P10253 1/20 0.32
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765460 0.82 CDC25B (0.33) CDC25BGAANPC1MAOAMAOB
SCHEMBL2642826 0.77 NPC1 (0.41) GAANPC1POLB
SCHEMBL11710618 0.73 AXL (0.35) GAA
SCHEMBL8765469 0.73 KDM4E (0.36) GAANPC1POLBFDPS
SCHEMBL30802769 0.71 KDM4C (0.48) GAANPC1POLB
SCHEMBL9017991 0.70 SIRT3 (0.55) GAANPC1POLB
SCHEMBL323164 0.69
SCHEMBL8765465 0.68 KDM4E (0.36) GAAFDPS
SCHEMBL7190827 0.65 TSHR (0.39)
SCHEMBL8116202 0.65 CYP19A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778267-A1 SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-11 EP disclosed